Job Description

Principal Scientist Platform Biology/Data Generation

Somerville, MA USA

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way.

What this position is all about :

Cellarity is seeking an experienced and highly motivated Principal Scientist with expertise in Functional Genomics and Next Generation Sequencing (NGS) to play a vital role in the companys efforts to enhance and expand our perturbation data engine. The candidate will be responsible for planning and executing large-scale data generation efforts, working with CROs and managing junior scientists. The successful candidate will work cross-functionally, particularly with our Machine Learning, and Biology teams to build meaningful datasets that drive our Foundation Models. The ideal candidate must be independent, goal oriented, have excellent communication skills, be willing to learn new skills and work in a fast-paced entrepreneurial environment.

What you would be responsible for:

• Lead from the bench data generation efforts to support our expanding platform capabilities
• Plan and execute Next Generation Sequencing (NGS) experiments
• Develop and execute CRISPR based perturbation screens
• Manage CROs and mentor junior scientists
• Collaborate with scientists from Machine Learning, Assay Development, and Exploratory Biology as part of our efforts to enhance our platform tools
• Maintain detailed records of experimental protocols and data in electronic laboratory notebooks
• Represent Platform Biology as a Biology Lead in Platform expansion efforts

What experiences will you need:

• ; MS with 15+ years of experience will be considered
• Demonstrated ability leading projects and driving programs to key decisions points
• Extensive experience in Next Generation Sequencing methodologies including single cell transcriptomics
• Experienced managing CROs, including transfer and implementation of SOP and assays
• Previous experience performing CRISPR screens (pooled or arrayed)

What sets you apart:

• Led a project team with 5-10 members
• Innovative mindset focused on pushing scientific boundaries
• Data-driven, willingness to abandon dogma when science leads us to new places
• Strong desire to work collaboratively within and across teams

What its like to work at Cellarity

At Cellarity, we

• Push Boundaries: We create a legacy with breakthrough science in service of patients.
• Inject Energy: We build strengths from different perspectives and tell it like it is
• Own it: We transcend our job descriptions and relentlessly follow through on our commitments.
• Go all out: We work quickly and with conviction.

Company Summary: Cellaritys mission is to fundamentally redesign the way drugs are created for the sake of bringing new hope to patients. By shifting the focus from a single target to the underlying cellular dysfunction, we unravel the complexity of disease biology and create medicines that were never before possible. The company has developed unique capabilities that link biology and chemistry with high dimensional -omic data from which we design medicines against the cellular signature of disease. The Cellarity platform allows us to uncover new biologyin diseases even in the absence of known causal targets. Cellarity is a privately held, clinical-phase drug discovery startup using AI and single-cell omics to develop life-changing medicines that are unreachable by traditional methods of drug discovery. Cellarity is a product of Flagship Pioneering's venture creation engine, which has conceived and created companies such as Moderna (NASDAQ: MRNA), Generate: Biomedicines, and Lila Sciences.

Cellarity is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies : Cellarity does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Cellarity or its employees is strictly prohibited unless contacted directly by Cellaritys internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Cellarity, and Cellarity will not owe any referral or other fees with respect thereto.

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